Skingenetix PDRN 1% Collagen Night Cream, 50ml - jar on a white background

Skingenetix PDRN 1% Collagen Night Cream, 50ml - open jar with a swatch of the pink cream

Skingenetix PDRN 1% Collagen Night Cream, 50ml - jar beside its pink and silver carton

Skingenetix PDRN 1% Collagen Night Cream, 50ml - jar resting on cream silk

Skingenetix PDRN 1% Collagen Night Cream, 50ml - jar on a colour-block pedestal

Skingenetix PDRN 1% Collagen Night Cream, 50ml - stacked jars from the Skingenetix range

PDRN 1% Collagen Night Cream

€89,00

An overnight cream pairing PDRN with hydrolyzed collagen and copper peptide for a firmer, smoother, more revitalised-looking complexion by morning.

PDRN (Sodium DNA) + Hydrolyzed Collagen - a revitalising overnight duo
Supports a firmer, smoother, more revitalised-looking complexion
No parabens · no mineral oil · no synthetic fragrance

Best for: skin that looks tired or less firm and wants to wake up plumper, smoother and more revitalised.

Size: 50ml

Key Benefits

Overnight revitalisation - for a fresher, more rested-looking complexion
Firms & smooths - PDRN and collagen for firmer, smoother-looking skin
Nourishes - a rich overnight texture with squalane
Supports renewal - helps skin look renewed by morning

What to expect: a fresher, more rested look by morning; firmer, smoother-looking skin with nightly use.

How to Use

Use in the evening as the final step in your routine. Massage a pea-sized to two-pea-sized amount (more for dry skin) over the face and neck to seal in your evening serums. Its rich, overnight texture nourishes the skin while you sleep.

For a complete overnight routine, apply after the PDRN Renewal Serum.

Key Ingredients

PDRN (Sodium DNA)
Hydrolyzed Collagen
Copper Tripeptide-1
Niacinamide
Hyaluronic Acid

Clinical Research

Clinical research suggests that PDRN (polynucleotides from salmon DNA) can support the look of firmer, smoother skin, including:

~20% reduction in the appearance of crow's feet (early split-face study, vs a retinol cream)
Support for skin firmness, elasticity and under-eye smoothness
Renewal-related signalling via the adenosine A2A receptor

PDRN (INCI: Sodium DNA) is a well-studied skin-conditioning ingredient in skin science.

Quantity:

Clinically Studied Ingredients

Fast Worldwide Shipping

Secure Online Payment

€89,00

Before and after

Photographed by customers at home, weeks apart.

Before

After

Gabrielle D

Verified Customer

I recommend this PDRN cream

I buy this PDRN cream for the autumn and winter. It is perfect for mature, sensitive skin with rosacea. It calms and strengthens the skin barrier. Although my skin is acne-prone, it doesn't clog my pores or cause breakouts. A perfect choice in winter and whenever the skin needs repairing.

Before

After

Danielle S

Verified Customer

It repairs and hydrates

After a week of using it in the evening, my skin still feels soft the day after applying. It works beautifully as a night cream because it gives my dry skin enough moisture. My skin also has a lovely sheen.

Before

After

Lana D

Verified Customer

It saved my skin

It really saved my skin. I can see a big difference after one month.

Before

After

Madeline W

Verified Customer

A beautiful product

I have had problems with dry, itchy skin, and this product has really helped my skin feel better.

Before

After

Mara F

Verified Customer

So far I like it a great deal

I have tried several PDRN creams and this one from Skingenetix is much better. I love the texture, which is light and super hydrating. My combination skin doesn't get oily from this cream, and it sits beautifully under SPF and make-up.

Before

After

Brenda S

Verified Customer

A very good cream

The cream has a rich consistency. In winter I use it both during the day and in the evening; in summer only in the evening, because it can be a little much to wear sunscreen on top. It hydrates well and my skin feels soft and full in the morning and through the day.

Before

After

Marion H

Verified Customer

It sinks in beautifully and hydrates

Creamy and very hydrating. You need very little product each time. It leaves the skin soft and lovely, and it penetrates very well.

Before

After

Livia B

Verified Customer

The glow of time

This cream came warmly recommended by a friend and I had to try it myself. The consistency is cool and supple and absorbs straight away, and the skin feels extremely hydrated and radiant. I felt reborn and I will definitely buy it again.

Before

After

Stephanie M

Verified Customer

An absolute game changer for the skin barrier

Fantastic cream. It hydrates deeply and calms the skin barrier perfectly. It absorbs quickly and leaves a wonderful, smooth texture. Highly recommended.

Frequently Asked Questions

Skingenetix pdrn collagen repair night cream

Our customer support is available Monday to Friday: 8am-8:30pm.

Average answer time: 24h

What does the PDRN 1% Collagen Night Cream do?

A rich overnight moisturiser with PDRN (Sodium DNA), collagen, copper peptide, niacinamide and hyaluronic acid. Used at night, it deeply hydrates and supports firmer, plumper and smoother-looking skin by morning.

What is PDRN (Sodium DNA)?

PDRN, shown on the INCI as Sodium DNA, is a salmon-derived ingredient popular in Korean skincare. In cosmetics it is valued for its hydrating, skin-conditioning properties that help skin look smoother and more refreshed. This cream contains 1% PDRN (Sodium DNA), or 10,000 ppm.

When and how do I apply it?

This is an evening step. After cleansing (and your serum), warm a pea-sized amount and press gently into face and neck as the final step of your night routine. Use nightly.

Can I use it with the PDRN Renewal Serum?

Yes, they are designed to layer. Apply the PDRN Renewal Serum first, let it absorb for about 60 seconds, then seal with the night cream.

Is it vegan?

No. PDRN (Sodium DNA) is salmon-derived and the formula contains collagen of animal origin, so it is not suitable for a vegan routine. It is free from parabens and mineral oil.

Is it suitable for sensitive skin?

It is formulated without parabens, mineral oil or added synthetic fragrance, and contains lightweight silicones for a smooth finish. As with any new product, we recommend a patch test first.

How to Use

3 Simple Steps

1. Cleanse

Wash with a gentle, pH-balanced cleanser and pat skin dry.

Close-up of a woman with her eyes closed applying Skingenetix PDRN 1% Renewal Serum to her cheek with a glass dropper, holding the 30ml frosted pink bottle

2. Apply your serum

Apply your Skingenetix serum and allow it to absorb.

Close-up of a model smoothing a pale pink repair cream along her cheekbone with two fingertips

3. Seal with the Night Cream

Press gently into face and neck as the final step of your evening routine.

The Skingenetix Standard

High Purity Ingredients

Pharmaceutical-grade actives. No fillers, no fragrance, no compromise.

Multi-Peptide Approach

Each product targets a different biological pathway. Layer safely for comprehensive results - the same principle behind clinical combination therapy.

Backed by Published Research

Every active is chosen from peer-reviewed studies - cited on our research pages.

Clean, Minimal Formulas

No parabens, no mineral oil and no added synthetic fragrance.

Science, Not Hype

Every formula is built on published clinical research - not trends, not influencer hype. That's the difference.

PDRN 1% Collagen Night Cream

Before and after

Frequently Asked Questions

3 Simple Steps

The Skingenetix Standard

Complete Your Routine