Laboratory glassware on a dark bench holding blue and rose-pink solutions beside a clear test tube, with scientific equipment out of focus behind

Skingenetix bases every claim on published research. Here we take the trials behind our ingredients and read each one in full: what was tested, what it found, and how to read the result.

Clinical studies

Fine rose-coloured strands drifting across a dark graphite ground
PDRN

Does PDRN after microneedling smooth wrinkles around the eyes faster?

In a randomised split-face trial of 29 women, PDRN microneedling eased wrinkles around the eyes in 2 months; microneedling with saline took 6.

MatrixylClose-up of a network of fine teal fibres

Does palmitoyl pentapeptide-4 reduce fine lines and wrinkles?

In a split-face trial of 93 women, 3 ppm palmitoyl pentapeptide-4, the original Matrixyl®, reduced fine lines and wrinkles more than placebo from week 8.

GHK-CuBlue copper peptide (GHK-Cu) crystals in a glass dish beside a flask and a beaker of blue solution and a microscope

Does a copper peptide serum reduce wrinkles?

Wrinkle volume fell 24.1% against 15.0% with the plain base, and 31.6% more than with a Matrixyl 3000 product, in an 8-week trial of 40 women.

PDRNClear, thread-like strands tangled in a pink gel, close up

Can PDRN outperform retinol on crow's feet?

In a split-face trial of 31 women, a 0.1% PDRN eye cream softened crow's feet by up to 23% in 28 days, more than three times as much as 0.1% retinol.

ArgirelineClear peptide crystals on a dark glass slide, close up

Does Argireline® soften crow's feet?

In a double-blind trial of 60 adults with crow's feet, nearly half of those on 10% Argireline were graded clearly smoother in 4 weeks, none on placebo.

Before you try it

These articles summarise published studies. They are not medical advice, and your own results may differ. Our products are cosmetics. As with anything new for your skin, try a small amount on your inner forearm for 24 hours first, and add one new product at a time. Stop using it if you notice redness, itching, burning or swelling. If irritation continues, or if you have a skin condition, are pregnant or breastfeeding, or use prescription skin treatments, please ask your doctor or pharmacist before starting.

PDRN is derived from salmon. If you have a fish allergy, please speak to your doctor before using it, and try a small amount on your forearm first.

Studies by ingredient

Every study we cite, graded, is listed on the research page of its ingredient: Copper peptide (GHK-Cu), Matrixyl 3000, Argireline®, PDRN, Glutathione.

The products made with these five ingredients are in our shop.